BioLeonhardt Technology

BioLeonhardt Heart Regeneration Technology Platform

1. Bioelectric stimulator.

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2. Micro infusion pump.

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3. BL-15 Heart Regeneration Composition

Patented and Patent Pending Bioelectric Signals and Sequences

1. SDF-1 = stem cell homing.
2. IGF-1 = DNA repair and regeneration.
3. HGF = regeneration.
4. EGF = regeneration.
5. PDGF = regeneration and stem cell homing.
6. VEGF = blood vessel growth.
7. CCXL5 = blood vessel growth.
8. HIF1a = blood vessel growth.
9. eNOS = blood vessel dilatation.
10. Folistatin = muscle regeneration.
11. Tropoelastin = tissue elasticity.
12. ILs = inflammation management.
13. GDF-10 & 11 = regeneration.
14. Activin A+B = regeneration.
15. Stem cell proliferation.
16. Stem cell differentiation into beating pumping muscle.
17. Blood pressure management.

BL-15 Mixed Stem Cell Based Heart Regeneration Composition

1. Stem cells.
2. Immature myoblasts.
3. Selected exosomes.
4. Selected micro RNAs.
5. Selected alkaloids.
6. Selected growth factors.
7. Amniotic fluid.
8. Platelet Rich Fibrin (PRF)
9. Follistatin.
10. SDF-1.
11. Tropoelastin.
12. Engineered nutrient hydrogel.
13. IGF-1.
14. PDGF.
15. Heart matrix.

Micro Bioelectric Implantable Stimulator
510K FDA Market Cleared Bench Top Stimulator
FDA 510K Market Cleared Portable Wearable Stimulator
Micro Infusion Pump

Refillable under skin infusion pump

Prototype combination bioelectric stimulation and infusion catheter

BioLeonhardt building the ultimate team alliance of all-star collaboration partners.

BioLeonhart is building an alliance of technology partners to build its platform.

These include:

1. Biomerics Advanced Catheter = pacing infusion leads.
2. QIG Greatbatch = micro stimulator OEM manufacturing.
3. Mettler Electronics = bench top stimulator OEM manufacturing.
4. Prizm Medical/Weartech Therapeutics = wearable stimulators.
5. USTAR BioInnovations Gateway Utah = research lab space and resources.
6. Cardiovascular Research and Training Institute = research pre-clinical.
7. Los Angeles Biomedical Research Institute = research pre-clinical.
8. CalTech California Institute of Technology = research.
9. LABioHub = Los Angeles area biomedical development resources.
10. BioUtah = Life sciences resources and connections Utah.
11. Fluid Synchrony LLC = micro infusion pumps.
12. Axolotl Biologix = amniotic fluid supply.
13. Reems Lab Utah = amniotic fluido supply.
15. Miron Lab Miami = PRF supply.
16. Chalmers Lab Santa Rosa, CA = Frequency specific microcurrent algorithms.
17. Trask & Britt Utah = patent services.
18. Ledgergurus = accounting services.
19. CapShare = stakeholder management services.
20. Worthworm = Pre-money valuation services.
21. Asana = Project management software.
22. Tissue Genesis Inc. = automated cell harvesting devices.
23. U.S. Stem Cell, Inc. = manual cell harvesting kits.
24. UCLA Molecular Imaging Lab = imaging servides pre-clinical.
25. Dr. Doris Taylor Lab Texas Heart Institute = research collaboration and consulting.
26. Dr. Stuart Williams Lab Cardiovascular Innovation Institute Louisville = research consultation.
27. Second Heart Assist, Inc. = circulatory assist devices aorta www.secondheartinc.com

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